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. 2021 Aug 17;13:686066. doi: 10.3389/fnagi.2021.686066

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Copyright © 2021 Huang, Liu, Hu, Han, Zhong, Luo, Zhang and Ling.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Four immune cell fractions in the blood from PD compared with those from HC are significantly different and the correlation between immune cells and DEGs in the blood of patients with PD. (A) The main immune cell fractions in the blood from PD and HC. The ordinate represents the immune cell fractions, and the abscissa represents the immune cell types. The blue dots represent HC samples, and the red dots represent PD samples. (B) KEGG pathway–NK cell-mediated cytotoxicity enriched in PD using GSEA. (C) Correlation between PTGDS and immune cells. (D) Correlation between MMP9 and immune cells. *p < 0.05, **p < 0.01.