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. 2021 Aug 18;8:682107. doi: 10.3389/fmed.2021.682107

Table 2.

Diagnostic efficacy of the different diagnostic methods for TBTB patients.

Sensitivity % Specificity % NPV % PPV %
95% CI 95% CI 95% CI 95% CI
Xpert MTB/RIF assay 87.2
0.811–0.915
97.7
0.912–0.996
78.7
0.696–0.858
98.7
0.950–0.998
in BALF 156/179 85/87 85/108 156/158
MTB Culture 84.9α 97.7 75.9 98.7
in BALF 0.786–0.897 0.912–0.996 0.667–0.833 0.949–0.998
152/179 85/87 85/112 152/154
Brushing smear microscopy 35.2β
0.283–0.427
98.9
0.929–0.999
42.6γ
0.357–0.497
98.4
0.905–0.999
63/179 86/87 86/202 63/64

TBTB, tracheobronchial tuberculosis; CI, confidence interval; MTB, Mycobacterium tuberculosis; RIF, rifampin; BALF, bronchoalveolar lavage fluid.

α

Compared with the Xpert MTB/RIF assay in BALF: χ2 = 0.372, p = 0.542.

β

Compared with the Xpert MTB/RIF assay: χ2 = 101.716, p = 0.000.

γ

Compared with the Xpert MTB/RIF assay in BALF: χ2 = 37.141, p = 0.000.