Table 2.

Enroll-HD data elements and assessments.

Data element/assessment	Corea	Extendedb	Optionalc
General
Investigator determined classification of participant	X
Sociodemographic data	X
HD clinical characteristics	X
Medical history	X
Comorbid conditions	X
Current therapies (pharmacotherapies, non-pharmacologic therapies, and nutritional supplements)	X
Reportable event monitoring	X
Motor
UHDRS '99 Motor	X
UHDRS '99 Diagnostic Confidence Index	X
Timed Up and Go		X
30 second Chair Stand Test		X
Function
UHDRS '99 Total Functional Capacity	X
UHDRS '99 Function Assessment Scale	X
UHDRS '99 Independence Scale	X
Behavior
Problem Behaviors Assessment (Short)	X
Hospital Anxiety and Depression Scale		X
Snaith Irritability Scale		X
Columbia Suicide Severity Rating Scale		X
Cognition
Symbol Digit Modality Test	X
Stroop Word Reading Test	X
Verbal Fluency Test (Category)	X
Stroop Color Naming Test	X
Stroop Interference Test		X
Trail Making Tests (Parts A and B)		X
Verbal Fluency Test (Letters)		X
Mini Mental State Examination		X
Global assessment
Clinical Global Impression		X
Quality of Life
Short Form Health Survey 12v2		X
Caregivers Quality of Life Questionnaire		X
Health Economics
Client Services Receipt Inventory		X
Work Productivity and Activity Impairment-Specific Health Problem		X
Genotyping
Research CAG genotyping	X
Local CAG genotyping (predictive/diagnostic) (if applicable)
Family history			X
Biosample donation			X

^aCompleted or updated at each annual visit.

^bCompleted at the discretion of the principal investigator.

^cCompleted at the discretion of the participant.