Table 3.
Enroll-HD participant characteristics - sociodemographic and basic disease variables (PDS5 dataset; release 2020-10-31v1).
| Total participants | HDGECs | Controls | |
|---|---|---|---|
| Number of participants | 21,116 | 16,120 | 4,996 |
| Sex, female; N (%) | 11,783 (56%) | 8,727 (54%) | 3,056 (61%) |
| Age at baseline; mean (SD) | 47.9 (14.0) | 48.7 (14.0) | 46.7 (14.8) |
| Education level (ISCEDa; 0–3); N (%) | 10,119 (48.1%) | 8,130 (50.7%) | 1,989 (40.0%) |
| Mean CAG length (SD) | N/A | 43.6 (4.1) | 20.2 (3.6) |
| CAP scoreb at baseline; mean (SD) | N/A | 97.2 (24.0) | N/A |
a
ISCED education level dichotomized into binary variable: 0–3 and 4–6. Precise definitions for these categories vary by country. In the UK, 0–3 captures everything up to and including sixth form (i.e., further education), 4–6 captures university and beyond (i.e., higher education).
b
CAP score calculated using the formula CAP = AGE × (CAG−30)/6.49, which is standardized such that CAP = 100 at estimated age of disease onset.