Figure 9.
(A) Schematic representation of the synthesis of the polyglycerol amine functionalized graphene sheets (GA), polyglycerol sulfate-functionalized graphene sheets (GS) and conjugation of pH-sensitive dye to the GA and GS (GAD, GSD). Information regarding the synthesis these graphene platforms can be found in ref.166 In vitro release profile of DOX from the GAD (B) and GSD (C) at 37 °C in various media.
Notes: Reproduced with permission of Royal Society of Chemistry from Tu Z, Wycisk V, Cheng C, Chen W, Adeli M, Haag R. Functionalized graphene sheets for intracellular controlled releaseof therapeutic agents. Nanoscale. 2017;9:18931–18939.131 Copyright 2017, Advanced Functional Materials; permission conveyed through Copyright Clearance Center,Inc.