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. 2021 Aug 18;12:727681. doi: 10.3389/fmicb.2021.727681

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Copyright © 2021 Zhai, Niu, Liu, Lin and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Oral administration of ELE regulated the bile acids through gut microbiota regulatory effect in mice. (A) Content of total BA in serum. (B) The content of total primary BA in serum. (C) Content of total secondary BA in serum. (D) Ratio of primary bile acid to secondary bile acid content in serum. (E) Qualitative and quantitative analysis of primary bile acids. (F) Qualitative and quantitative analysis of secondary bile acids. (G) Correlation analysis of gut microbiota and bile acids. *p < 0.05; **p < 0.01; ***p < 0.001.