Table 2.

Factors for Alzheimer dementia by using the analysis of Fine and Gray's competing risk model.

	Competing risk in the model
Variables	Crude HR	95% CI	95% CI	P	Adjusted HR	95% CI	95% CI	P
Chlamydia pneumonia (reference: without)	1.676	1.425	1.902	<0.001	1.599	1.284	1.971	<0.001
Male (reference: female)	1.182	1.007	1.387	0.041	1.164	0.989	1.369	0.067
Hyperlipidemia (reference: without)	1.497	1.298	1.830	<0.001	1.427	1.252	1.724	0.002
Coronary artery disease (reference: without)	1.492	1.396	1.657	<0.001	1.478	1.357	1.640	<0.001
Hypertension (reference: without)	0.843	0.713	1.007	0.064	1.060	0.723	1.222	0.087
Cancer (reference: without)	0.376	0.265	0.535	<0.001	0.400	0.280	0.572	<0.001
Depression (reference: without)	2.066	1.106	3.860	0.023	1.551	0.825	2.917	0.173
Anxiety (reference: without)	1.627	1.333	1.901	<0.001	1.638	1.394	1.926	<0.001
Alcohol use disorder (reference: without)	5.351	2.001	14.311	0.001	5.778	2.138	15.637	0.001
Sleep disorder (reference: without)	2.090	1.180	3.701	0.011	2.011	1.129	3.584	0.018
CCI_R 1 (reference: CCI_R: 0)	1.546	1.303	1.835	<0.001	1.353	1.134	1.615	0.001
CCI_R 2 (reference: CCI_R: 0)	1.348	1.036	1.745	0.026	1.081	0.826	1.415	0.599
CCI_R 3 (reference: CCI_R: 0)	1.759	1.201	2.576	0.004	1.436	0.976	2.113	0.066
Autumn (reference: Spring)	0.744	0.593	0.933	0.011	0.704	0.560	0.885	0.003
Medical center (reference: local hospital)	1.689	1.570	1.832	<0.001	1.692	1.569	1.842	<0.001
Regional hospital (reference: local hospital)	1.620	1.503	1.764	<0.001	1.645	1.510	1.815	<0.001

HR, hazard ratio; CI, confidence interval; Adjusted HR, adjusted variables listed in the Table 1; CCI_R, Charlson Comorbidity Index, dementia removed; P: Chi-square/Fisher exact test on category variables and t-test on continue variable.