Table 3.
Resistance to antimicrobial agents in the ESBL producers
| Antimicrobial agents | No. (%) of isolates | p- value of | ||||||
|---|---|---|---|---|---|---|---|---|
| CIPR | CIPS | |||||||
|
|
|
|||||||
|
ST131
(n= 33) |
non-ST131
(n= 27) |
ST131
(n= 15) |
non-ST131
(n= 19) |
CIPR
(ST131 vs. non-ST131) |
CIPS
(ST131 vs. non-ST131) |
AS
(CIPR non-ST131 vs. CIPS non-ST131) |
AS
(CIPR ST131 vs. CIPS ST131) |
|
| AUG | 24 (73) | 14 (52) | 8 (53) | 12 (63) | 0.095 | 0.728 | 0.446 | 0.186 |
| SAM | 23 (70) | 12 (44) | 2 (13) | 7 (37) | 0.048 | 0.123 | 0.606 | < 0.0001 |
| PTZ | 11 (33) | 8 (29) | 1 (7) | 4 (21) | 0.759 | 0.240 | 0.514 | 0.048 |
| ATM | 32 (97) | 21 (77) | 13 (87) | 13 (68) | 0.047 | 0.312 | 0.477 | 0.172 |
| SXT | 26 (79) | 22 (81) | 11 (73) | 15 (79) | 0.795 | 0.732 | 0.831 | 0.677 |
| GM | 20 (61) | 8 (30) | 3 (20) | 1 (5) | 0.017 | 0.185 | 0.040 | 0.009 |
| AN | 5 (15) | 3 (11) | 1 (7) | 2 (10) | 0.647 | 0.694 | 0.950 | 0.410 |
| IN | 3 (9) | 5 (18) | 3 (20) | 2 (10) | 0.265 | 0.439 | 0.457 | 0.289 |
AS, Antimicrobial susceptibility; AUG, amoxicillin-clavulanic acid; SAM, ampicillin-sulbactam; PTZ, piperacillin-tazobactam; ATM, aztreonam; SXT, trimethoprim-sulfamethoxazole; GM, gentamicin; AN, amikacin; IN, nitrofurantoin; CIPR, fluoroquinolone resistant; CIPS, fluoroquinolone sensitive. The CIPR isolates studied were defined as resistant isolates to ciprofloxacin. The ESBL positive isolates studied were confirmed by the combined disk test (CDT) as ESBL producers. All the isolates were susceptible to carbapenems and resistant to cefotaxime and nalidixic acid.
A p-value ≤ 0.05 was consideredstatistically significant.