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. 2021 Aug 18;13:694254. doi: 10.3389/fnagi.2021.694254

Table 4.

Differences in nodal network measures from the cognitive connectome across age groups.

Early-middle-age vs. Elderly Early-middle-age vs. Late-middle-age Late-middle-age vs. Elderly
Global Efficiency PCV Motor time ↑(0.006) n.s ↑(<0.001)
PCV Decision time ↑(0.006) n.s ↑(<0.001)
CTT-Part 1 ↓(0.006) n.s n.s
HT 1st trial ↑(0.006) n.s n.s
HT Learning ↑(0.006) n.s n.s
HT Long delay ↑(0.006) n.s n.s
FRT n.s n.s ↑(<0.001)
Local Efficiency PCV Motor time n.s ↓(<0.001) n.s
PCV Decision time ↓(<0.001) ↓(<0.001) n.s
HT Long delay ↑(<0.001) n.s ↑(<0.001)
CTT-Part 1 ↓(<0.001) ↓(<0.001) n.s
STROOP Words ↓(<0.001) n.s n.s
STROOP Inhibition n.s n.s ↓(<0.001)
Semantic fluency n.s n.s ↓(<0.001)
Participation STROOP Words n.s ↑(0.003) n.s
STROOP Colors ↑(0.006) ↑(0.003) n.s
STROOP Inhibition ↑(0.006) n.s n.s
Block Design Total ↑(0.006) n.s n.s
Nodal Strength PCV Motor time ↑(<0.001) n.s ↑(<0.001)
PCV Decision time ↓(<0.001) n.s n.s
CTT-Part 1 ↓(<0.001) n.s n.s

Each column shows between-group differences in local network measures, with the first group as the reference group in the comparison: higher values in the second group in the comparison are indicated with an upwards arrow (e.g., in the “Early-middle-age vs. Elderly” comparison, an upwards arrow indicates that PCV motor time shows a higher global efficiency in the Elderly group than the Early-middle-age group), lower values in the second group in the comparison are indicated with a downwards arrow, and n.s denotes non-significant results. False discovery rate (FDR) adjustment was used at p ≤ 0.05 (two-tailed) for analyses. FDR adjusted p-value within parentheses. PCV, PC-Vienna System; CTT, Color Trails Test; HT, Hanoi Tower; FRT, Facial Recognition Test.