Table 4.
Differences in nodal network measures from the cognitive connectome across age groups.
| Early-middle-age vs. Elderly | Early-middle-age vs. Late-middle-age | Late-middle-age vs. Elderly | ||
|---|---|---|---|---|
| Global Efficiency | PCV Motor time | ↑(0.006) | n.s | ↑(<0.001) | 
| PCV Decision time | ↑(0.006) | n.s | ↑(<0.001) | |
| CTT-Part 1 | ↓(0.006) | n.s | n.s | |
| HT 1st trial | ↑(0.006) | n.s | n.s | |
| HT Learning | ↑(0.006) | n.s | n.s | |
| HT Long delay | ↑(0.006) | n.s | n.s | |
| FRT | n.s | n.s | ↑(<0.001) | |
| Local Efficiency | PCV Motor time | n.s | ↓(<0.001) | n.s | 
| PCV Decision time | ↓(<0.001) | ↓(<0.001) | n.s | |
| HT Long delay | ↑(<0.001) | n.s | ↑(<0.001) | |
| CTT-Part 1 | ↓(<0.001) | ↓(<0.001) | n.s | |
| STROOP Words | ↓(<0.001) | n.s | n.s | |
| STROOP Inhibition | n.s | n.s | ↓(<0.001) | |
| Semantic fluency | n.s | n.s | ↓(<0.001) | |
| Participation | STROOP Words | n.s | ↑(0.003) | n.s | 
| STROOP Colors | ↑(0.006) | ↑(0.003) | n.s | |
| STROOP Inhibition | ↑(0.006) | n.s | n.s | |
| Block Design Total | ↑(0.006) | n.s | n.s | |
| Nodal Strength | PCV Motor time | ↑(<0.001) | n.s | ↑(<0.001) | 
| PCV Decision time | ↓(<0.001) | n.s | n.s | |
| CTT-Part 1 | ↓(<0.001) | n.s | n.s | 
Each column shows between-group differences in local network measures, with the first group as the reference group in the comparison: higher values in the second group in the comparison are indicated with an upwards arrow (e.g., in the “Early-middle-age vs. Elderly” comparison, an upwards arrow indicates that PCV motor time shows a higher global efficiency in the Elderly group than the Early-middle-age group), lower values in the second group in the comparison are indicated with a downwards arrow, and n.s denotes non-significant results. False discovery rate (FDR) adjustment was used at p ≤ 0.05 (two-tailed) for analyses. FDR adjusted p-value within parentheses. PCV, PC-Vienna System; CTT, Color Trails Test; HT, Hanoi Tower; FRT, Facial Recognition Test.