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. Author manuscript; available in PMC: 2022 Oct 1.
Published in final edited form as: AIDS. 2021 Oct 1;35(12):1949–1956. doi: 10.1097/QAD.0000000000002981

Table 2.

Odds ratio for risk of future HIV viral load ≥20 copies/mL by concentration of emtricitabine triphosphate (FTC-TP) in dried blood spots (DBS) at current visit (n=667 paired assessments).

FTC-TP Paired
assessments
n (%)
OR future viremia
(95% CI)
p-value *aOR future viremia
(95%; CI)
p-value
BLQ** 56 (8%) 4.1 (2.3, 7.2) <0.0001 3.4 (1.8, 6.5) 0.0002
Quantifiable 611 (92%) 1 REF 1 REF
Including TFV-DP in DBS
BLQ 56 (8%) 2.6 (1.3, 5.2) 0.006 1.9 (0.9, 4.1) 0.090
Quantifiable 611 (92%) 1 REF 1 REF

FTC-TP: emtricitabine triphosphate; BLQ: below limit of quantification; OR: odds ratio; aOR: adjusted odds ratio; 95% CI: 95% confidence interval; TFV-DP: tenofovir diphosphate.

*

Adjusted for age, gender, race, body mass index, estimated glomerular filtration rate, hematocrit, CD4+ T-cell count, and ART class.

**

FTC-TP in DBS was considered BLQ if it was <0.1 pmol/sample.