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. 2021 Aug 19;17(13):3608–3621. doi: 10.7150/ijbs.64003

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Downregulation of CDC20 also significantly suppressed proliferation, promoted apoptosis, and increased cell cycle arrest at the G2/M phase of Hep3B cells. A. The protein level of CDC20, apoptosis and cell cycle related proteins with different treatments was detected by WB. B. MTS assays detected the cell proliferation of each group. C. The apoptosis percentages of each group were measured by flow cytometry. D. Flow cytometry was used to determine the percentage of cell cycle. Data are presented as means ± SD. *P < 0.01 indicated difference had statistical significance versus the siNC.