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. 2021 Jul 25;17(13):3288–3304. doi: 10.7150/ijbs.63300

Table 1.

Correlations between N-cadherin expression and PCa patients' clinical characteristics.

Clinicopathological parameters Total (n = 60) (%) N-cadherin expressiona P-value
S-Tb/M-Wc2d test
Low (%) High (%)
Age
Median (IQR) 66 (61-69.75) 66 (59-68.25) 66.5 (62.75-71) 0.191b
Range (Min, Max) 55-76 55-76 57-75
< 65 24 (40.0%) 13 (43.3%) 11 (36.7%) 0.598d
≥ 65 36 (60.0%) 17 (56.7%) 19 (63.3%)
Log2 NDRG1 expressiona
Median (IQR) -12.4777
(-13.3336--11.6622)
-11.8416
(-12.5765--11.3095)
-13.069
(-13.5803--12.1849)
0.000b*
Range (Min, Max) -14.2934--10.5782 -14.2934--10.5782 -14.1577--11.507
Low 30 (50.0%) 8 (26.7%) 22 (73.3%) 0.000d
High 30 (50.0%) 22 (73.3%) 8 (26.7%)
Total PSA (t-PSA)
Median (IQR) 17.275
(8.5725-42.4225)
19.76
(8.3675-42.3)
16.285
(8.3325-43.8875)
0.918c
Range (Min, Max) 0.56-85.35 1.05-64.24 0.56-85.35
< 4 ng/ml 5 (8.3%) 3 (10.0%) 2 (6.7%) 0.517d
0.404c
4-10 ng/ml 15 (25.0%) 5 (16.7%) 10 (33.3%)
10-20 ng/ml 13 (21.7%) 7 (23.3%) 6 (20.0%)
> 20 ng/ml 27 (45.0%) 15 (50.0%) 12 (40.0%)
Gleason Score (GS)
< 7 20 (33.3%) 14 (46.7%) 6 (20.0%) 0.074d
0.028c*
7 20 (33.3%) 9 (30.0%) 11 (36.7%)
> 7 20 (33.3%) 7 (23.3%) 13 (43.3%)
Clinical T-stage
T2a 7 (11.7%) 5 (16.7%) 2 (6.7%) 0.282d
0.064c
T2b 14 (23.3%) 9 (30.0%) 5 (16.7%)
T2c 23 (38.3%) 10 (33.3%) 13 (43.3%)
T3a or T3b 16 (26.7%) 6 (20.0%) 10 (33.3%)
Lymph node metastasis
N0 44 (73.3%) 25 (83.3%) 19 (63.3%) 0.080d
N1 16 (26.7%) 5 (16.7%) 11 (36.7%)
Distant metastasis
M0 or Mx 53 (88.3%) 28 (93.3%) 25 (83.3%) 0.421d
M1 7 (11.7%) 2 (6.7%) 5 (16.7%)
TNM stage
I-II 35 (58.3%) 19 (63.3%) 16 (53.3%) 0.432d
III-IV 25 (41.7%) 11 (36.7%) 14 (46.7%)

* P < 0.05

a Median mRNA expression of N-cadherin as a cutoff.

b P-value (2-sided) of Student's t-test.

c P-value (2-sided) of the Mann-Whitney U test.

d P-value (2-sided) of Pearson chi-square test or continuity correction for the chi-square test.