Table 1.
Clinicopathological parameters | Total (n = 60) (%) | N-cadherin expressiona | P-value S-Tb/M-Wc/χ2d test |
|
---|---|---|---|---|
Low (%) | High (%) | |||
Age | ||||
Median (IQR) | 66 (61-69.75) | 66 (59-68.25) | 66.5 (62.75-71) | 0.191b |
Range (Min, Max) | 55-76 | 55-76 | 57-75 | |
< 65 | 24 (40.0%) | 13 (43.3%) | 11 (36.7%) | 0.598d |
≥ 65 | 36 (60.0%) | 17 (56.7%) | 19 (63.3%) | |
Log2 NDRG1 expressiona | ||||
Median (IQR) | -12.4777 (-13.3336--11.6622) |
-11.8416 (-12.5765--11.3095) |
-13.069 (-13.5803--12.1849) |
0.000b* |
Range (Min, Max) | -14.2934--10.5782 | -14.2934--10.5782 | -14.1577--11.507 | |
Low | 30 (50.0%) | 8 (26.7%) | 22 (73.3%) | 0.000d |
High | 30 (50.0%) | 22 (73.3%) | 8 (26.7%) | |
Total PSA (t-PSA) | ||||
Median (IQR) | 17.275 (8.5725-42.4225) |
19.76 (8.3675-42.3) |
16.285 (8.3325-43.8875) |
0.918c |
Range (Min, Max) | 0.56-85.35 | 1.05-64.24 | 0.56-85.35 | |
< 4 ng/ml | 5 (8.3%) | 3 (10.0%) | 2 (6.7%) | 0.517d 0.404c |
4-10 ng/ml | 15 (25.0%) | 5 (16.7%) | 10 (33.3%) | |
10-20 ng/ml | 13 (21.7%) | 7 (23.3%) | 6 (20.0%) | |
> 20 ng/ml | 27 (45.0%) | 15 (50.0%) | 12 (40.0%) | |
Gleason Score (GS) | ||||
< 7 | 20 (33.3%) | 14 (46.7%) | 6 (20.0%) | 0.074d 0.028c* |
7 | 20 (33.3%) | 9 (30.0%) | 11 (36.7%) | |
> 7 | 20 (33.3%) | 7 (23.3%) | 13 (43.3%) | |
Clinical T-stage | ||||
T2a | 7 (11.7%) | 5 (16.7%) | 2 (6.7%) | 0.282d 0.064c |
T2b | 14 (23.3%) | 9 (30.0%) | 5 (16.7%) | |
T2c | 23 (38.3%) | 10 (33.3%) | 13 (43.3%) | |
T3a or T3b | 16 (26.7%) | 6 (20.0%) | 10 (33.3%) | |
Lymph node metastasis | ||||
N0 | 44 (73.3%) | 25 (83.3%) | 19 (63.3%) | 0.080d |
N1 | 16 (26.7%) | 5 (16.7%) | 11 (36.7%) | |
Distant metastasis | ||||
M0 or Mx | 53 (88.3%) | 28 (93.3%) | 25 (83.3%) | 0.421d |
M1 | 7 (11.7%) | 2 (6.7%) | 5 (16.7%) | |
TNM stage | ||||
I-II | 35 (58.3%) | 19 (63.3%) | 16 (53.3%) | 0.432d |
III-IV | 25 (41.7%) | 11 (36.7%) | 14 (46.7%) |
* P < 0.05
a Median mRNA expression of N-cadherin as a cutoff.
b P-value (2-sided) of Student's t-test.
c P-value (2-sided) of the Mann-Whitney U test.
d P-value (2-sided) of Pearson chi-square test or continuity correction for the chi-square test.