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. 2021 Jul 25;17(13):3305–3319. doi: 10.7150/ijbs.63329

Figure 1.

Figure 1

The effect of RS-5645 on the activation of human PBMCs and the release of inflammatory factors induced by the S protein. (A) qPCR results indicated that the S protein induced the activation of human PBMCs and the upregulation of inflammatory factor gene mRNA expression. **p < 0.01 vs. 0 ng/ml; *p < 0.05 vs. 0 ng/ml; t-test; n = 3. (B) qPCR results indicated that RS-5645 significantly inhibited human PBMC activation and inflammatory factor gene mRNA expression. **p < 0.01 vs. 0 nM; *p < 0.05 vs. 0 nM; t-test; n = 3.