Table 2.
Distribution of 28 risk factors.
| Risk factor | Status | IC negative | IC positive | p value |
|---|---|---|---|---|
| Total | 7,865 | 137 | ||
| Age, mean (SD) | 57.3 (17.5) | 57.64 (17.52) | 0.859 | |
| Colonization (%) | No | 7,346 (93.4) | 93 (67.9) | <0.001 |
| Yes | 519 (6.6) | 44 (32.1) | ||
| Length of ICU stay, mean (SD) | 3.15 (5.58) | 13.70 (28.28) | <0.001 | |
| Length of hospital stay, mean (SD) | 7.19 (9.97) | 18.32 (29.27) | <0.001 | |
| Diabetes (%) | No | 6,331 (80.5) | 105 (76.6) | 0.308 |
| Yes | 1,534 (19.5) | 32 (23.4) | ||
| Acute kidney injury (%) | No | 4,461 (56.7) | 67 (48.9) | 0.081 |
| Yes | 3,404 (43.3) | 70 (51.1) | ||
| Pancreatitis (%) | No | 7,655 (97.3) | 133 (97.1) | 1.000 |
| Yes | 210 (2.7) | 4 (2.9) | ||
| Malignant tumor (%) | No | 6,424 (81.7) | 102 (74.5) | 0.040 |
| Yes | 1,441 (18.3) | 35 (25.5) | ||
| Sepsis(%) | No | 7,767 (98.8) | 133 (97.1) | 0.178 |
| Yes | 98 (1.2) | 4 (2.9) | ||
| History of fungal infection(%) | No | 7,859 (99.9) | 134 (97.8) | <0.001 |
| Yes | 6 (0.1) | 3 (2.2) | ||
| HIV(%) | No | 7,851 (99.8) | 137 (100.0) | 1.000 |
| Yes | 14 (0.2) | 0 (0.0) | ||
| BDG positive(%) | No | 7,684 (97.7) | 80 (58.4) | <0.001 |
| Yes | 181 (2.3) | 57 (41.6) | ||
| NEUT# ≤ 1.5 × 109/L(%) | No | 7,730 (98.3) | 128 (93.4) | <0.001 |
| Yes | 135 (1.7) | 9 (6.6) | ||
| Broad-spectrum antibiotic use (%) | No | 905 (11.5) | 6 (4.4) | 0.014 |
| Yes | 6,960 (88.5) | 131 (95.6) | ||
| Corticosteroid therapy or immunosuppressive use (%) | No | 6,140 (78.1) | 90 (65.7) | 0.001 |
| Yes | 1,725 (21.9) | 47 (34.3) | ||
| Chemotherapy drug use (%) | No | 7,808 (99.3) | 136 (99.3) | 1.000 |
| Yes | 57 (0.7) | 1 (0.7) | ||
| Total parenteral nutrition (%) | No | 6,296 (80.1) | 73 (53.3) | <0.001 |
| Yes | 1,569 (19.9) | 64 (46.7) | ||
| Mechanical ventilation (%) | No | 2,692 (34.2) | 28 (20.4) | 0.001 |
| Yes | 5,173 (65.8) | 109 (79.6) | ||
| Central venous catheter (%) | No | 2,096 (26.6) | 14 (10.2) | <0.001 |
| Yes | 5,769 (73.4) | 123 (89.8) | ||
| Renal replacement therapy (%) | No | 6,823 (86.8) | 93 (67.9) | <0.001 |
| Yes | 1,042 (13.2) | 44 (32.1) | ||
| Abdominal surgery (%) | No | 7,417 (94.3) | 117 (85.4) | <0.001 |
| Yes | 448 (5.7) | 20 (14.6) | ||
| Organ transplant (%) | No | 7,852 (99.8) | 137 (100.0) | 1.000 |
| Yes | 13 (0.2) | 0 (0.0) | ||
| Days of total parenteral nutrition mean (SD) | 0.50 (1.45) | 2.29 (3.60) | <0.001 | |
| Days of mechanical ventilation mean (SD) | 2.23 (3.04) | 5.43 (5.37) | <0.001 | |
| Days of central venous catheter mean (SD) | 2.96 (3.66) | 6.69 (5.73) | <0.001 | |
| Days of renal replacement therapy mean (SD) | 0.38 (1.41) | 1.57 (3.18) | <0.001 | |
| Sex (%) | Male | 4,811 (61.2) | 86 (62.8) | 0.769 |
| Female | 3,054 (38.8) | 51 (37.2) | ||
| LYM# ≤ 1 × 109/L (%) | No | 1,608 (20.4) | 8 (5.8) | <0.001 |
| Yes | 6,257 (79.6) | 129 (94.2) |