Skip to main content
. 2021 Aug 19;12:724170. doi: 10.3389/fpsyt.2021.724170

Table 2.

List of perpetrator medications responsible for CYP2D6, CYP2C19 and CYP2C9 phenoconversion identified at admission and discharge.

Medication No. of Patients Inhibitor Inducer Affected Enzyme(s)
Admission Discharge
Amiodarone 3 3 ✓ (M) CYP2C9
Carbamazepine 3 3 CYP2C9, CYP2C19
Duloxetine 11 13 ✓ (M) CYP2D6
Esomeprazole 19 17 ✓ (M) CYP2C19
Fluoxetine 2 1 ✓ (S) CYP2D6
✓ (M) CYP2C19
Omeprazole 4 4 ✓ (M) CYP2C19
Paroxetine 2 2 ✓ (S) CYP2D6
Sertraline 15 17 ✓ (M) CYP2D6
Terbinafine 1 0 ✓ (M) CYP2D6

The CYP inhibitor or inducer effect of each medication is listed along with the affected enzyme(s).

(S), Strong inhibitor; (M), Moderate inhibitor.