Table 2.
Ensemble Optimization Method (EOM) analysis of SAXS data. Fitting assessment between the experimental and theoretical scattering intensities generated by EOM for the pre-molten globule and the random coil ensembles. The CorMap test is a goodness-of-fit test [41].
| EOM analysis | ED-1 | ED-2 | ED-3 | ED-4 (monomer) |
|---|---|---|---|---|
| Pre-molten globule (PMG) model | ||||
| Reduced χ2 | 0.904 | 0.947 | 0.765 | 0.636 |
| CorMap p-value | 0.0002 | 0.000 | 0.008 | 0.004 |
| Random-coil (RC) model | ||||
| Reduced χ2 | 0.616 | 0.632 | 0.663 | 0.597 |
| CorMap p-value | 0.224 | 0.227 | 0.0645 | 0.0618 |
| Rflex ensemble (%) | 82.71 | 86.17 | 81.18 | 84.02 |
| Rflex pool (%) | 84.31 | 85.60 | 84.59 | 83.69 |
| Rσ | 0.92 | 2.47 | 0.85 | 1.01 |