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. 2021 Jul 21;26:333–346. doi: 10.1016/j.omtn.2021.07.007

Figure 2.

Figure 2

Targeting METTL3 expression impairs progression of ESCC in vitro

(A) Western blotting confirmation of METTL3 knockdown in TE-9 and TE-10 cells. (B) Growth of NC or shMETTL3 cells evaluated by CCK8. (C and D) Colony formation assay (C) and the quantification data (D) of TE-9 and TE-10 cells with or without METTL3 knockdown. (E and F) Wound healing assay (E) and the quantification data (F) of TE-9 and TE-10 cells with or without METTL3 knockdown. (G and H) Invasion assay (G) and the quantification data (H) of TE-9 and TE-10 cells with or without METTL3 knockdown. (I and J) Migration assay and the quantification data (J) of TE-9 and TE-10 cells with or without METTL3 knockdown. Data are represented as mean ± SD. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001 (one-way ANOVA; Student’s t test).