Figure 4.

8 weeks of supplemental linoleic acid diet attenuated, but not significantly, the doxycycline-induced alterations in (A) cardiolipin content but had no influence on (B) cardiolipin linoleic acid content or (C) MLCL:CL ratio in soleus of TazKD male mice compared to their wild-type littermates. Values are means ± SEM, n=2–6; no statistical difference between values with the same letter (p<0.05). CL, cardiolipin; WT, wild type; TazKD, Taz knockdown; Con, chow diet; and LA, linoleic acid-supplemented diet.