Figure A3.

Male single-fidelity multiscale arrhythmia risk classifier. Initial single high-fidelity exploration of the male drug-induced arrhythmogenic risk parameter space. The middle plot showcases 10 internal latin hypercube {β_Kr, β_CaL} sample evaluations of arrhythmogenesis in the male heart. The virtual electrocardiograms for one arrhythmogenic and three non-arrhythmic sample evaluations are shown in the left plots. The resulting exploratory male single high-fidelity drug-induced arrhythmogenic risk classifier is shown in the right plot.