Table 2.

Metabolic characteristics of gut microbiota in lung cancer.

Related metabolic pathway	Sample numbers	Sample type	References
RNA processing and modification↓	60	fecal specimens	He Zhuang et al. (1)
Chromatin structure and dynamics↓
extracellular structures↑
energy metabolism↓	46	fecal specimens	Fang Liu et al. (24)
ABC-type transport↓
cellular antigens↑	181	fecal specimens	Yajuan Zheng et al. (16)
steroid biosynthesi↑
ubiquitin system↑
transcription-related proteins↑
bile secretion↑
fatty acid elongation in mitochondria↑
bacterial motility proteins↓
bacterial chemotaxi↓
flavonol biosynthesis apoptosis and G protein-coupled receptors↓
dodecane↑	19	fecal specimens	Pamela Vernocchi et al. (53)
2,6-dimethyl-4 heptanone methyl
isobutyl ketone↑
aldehydes↓
ketones↓
terpenes ↓
p-cresol↓

↑, Metabolism increases in cases compared to controls; ↓, Metabolism decrease in cases compared to controls.