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. 2021 Sep 3;11:453. doi: 10.1038/s41398-021-01570-w

Table 1.

Characteristics of included reconsolidation studies.

Study Country Trauma sample Reconsolidation procedure Comparator No. of sessions n PTSD outcome Follow up Primary outcome
Adult pharmacological/ECT reconsolidation
Brunet et al. 2018* Canada Unspecified Propranolol & MR Placebo & MR 6 60 PTSD severity (CAPS & PCL-C) 1 week, 6 months 1 week PTSD severity
Wood et al. 2015 Study 1a USA Combat-related Propranolol & MR Propranolol 1 18 PTSD severity (IES-R) 1 week 1 week PTSD severity
Wood et al. 2015 Study 2a USA Combat-related Mifepristone & MR Mifepristone 1 28 PTSD Severity (IES-R) 1 week 1 week PTSD Severity
Wood et al. 2015 Study 3a USA Combat-related Mifepristone & d-cycloserine & MR Double placebo 1 31 PTSD severity (IES-R) 2 weeks 2 week PTSD severity
Suris et al. 2010a USA Combat-related Hydrocortisone & MR Placebo & MR 1 19 PTSD severity (IES-R) 1 week 1 week PTSD severity
Suris et al. 2013a USA Combat-related Sirolimus & MR Placebo & MR 1 51 PTSD severity (CAPS & PCL) 1, 3 months 1 & 3 month PTSD severity
Corchs et al. 2018a Brazil Unspecified ECT & MR (traumatic) ECT & MR (neutral) 6 8 PTSD severity (DTS) 1 month Skin conductance responses and subjective reactivity to trauma recollection
Adult psychological reconsolidation
Gray et al. 2017a USA Mixed RTM Waitlist control 3 69 PTSD severity (PCL-M) 2 weeks 2 week PTSD severity
Gray et al. 2015a USA Mixed RTM Waitlist control 3-5 31 PTSD severity (PCL-M) 2 weeks 2 week PTSD severity
Gray et al. Unpublisheda USA Mixed RTM Waitlist control ≤ 3 29 PTSD severity (PCL-M, PSS) 2 weeks 2 week PTSD severity
Tylee et al. 2017a USA Combat-related RTM Waitlist control 3 27 PTSD severity (PCL-M, PSS) 2 weeks 2 week PTSD severity

PTSD post-traumatic stress disorder, ASD acute stress disorder, n number of participants included at final assessment, CAPS clinician Administered PTSD scale, IES-R impact of events scale - revised, DTS Davidson trauma scale, PCL-C PTSD checklist - civilian version, PCL - M PTSD checklist - military version, PSS posttraumatic symptom scale, MR memory reactivation, RTM reconsolidation of traumatic memories.

aIncluded in meta-analysis.