Table 2.
Genotype frequencies of rs4341 and rs4343 polymorphisms in COVID-19 patients according to its hypertensive, dyslipidemic or diabetic status.
| rs4341 | ||||
|---|---|---|---|---|
| Hypertension | G/G | G/C | C/C | P-value |
| Hospital ward | 6 (20%) | 16 (53.3%) | 8 (26.7%) | 0.031* |
| ICU | 6 (50%) | 5 (41.7%) | 1 (8.3%) | 0.03 $ |
| Dyslipidemia | G/G | G/C | C/C | P-value |
| Hospital ward | 2 (15.4%) | 6 (46.1%) | 5 (38.5%) | 0.043* |
| ICU | 4 (57.1%) | 3 (42,9%) | 0 (0%) | |
| Diabetes Mellitus | G/G | G/C | C/C | P-value |
| Hospital ward | 1 (8.3%) | 7 (58.3%) | 4 (33.3%) | 0.033* |
| ICU | 3 (100%) | 0 (0%) | 0 (0%) | 0.009 $ |
| rs4343 | ||||
| Hypertension | G/G | G/A | A/A | P-value |
| Hospital ward | 15 (16.6%) | 17 (56.7%) | 8 (26.7%) | 0.03 % |
| ICU | 5 (41.7%) | 6 (50%) | 1 (8.3%) | |
| Dyslipidemia | G/G | G/A | A/A | P-value |
| Hospital ward | 2 (15.4%) | 6 (46.1%) | 5 (38.5%) | 0.043 # |
| ICU | 4 (57.1%) | 3 (42,9%) | 0 (0%) | |
| Diabetes Mellitus | G/G | G/A | A/A | P-value |
| Hospital ward | 1 (8.3%) | 7 (58.3%) | 4 (33.3%) | 0.033 # |
| ICU | 3 (100%) | 0 (0%) | 0 (0%) | 0.009 % |
Data are presented as number of patients and percentages.
*p-value for group difference between GG and GC and CC.
$p-value for group difference between GG+GC and CC.
#p-value for group difference between GG and GA and AA.
%p-value for group difference between GG+GA and AA.
Significant differences appear in bold case.
All data were adjusted for age, sex, BMI and number of comorbidities.