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. 2021 Aug 19;11:714866. doi: 10.3389/fonc.2021.714866

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Copyright © 2021 Liu, Zhang, Zhang, Qiu, Zhang and Han

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Prediction of hub genes-related transcription factor. (A) Potential binding site of TF and genes predicted with oPOSSum 3.0. (B) Expression correlation of TF and genes in four GEO series. (C) Significant positive correlation between ALB and FOXO3 expression and CDH2 and FOXO3 expression. (D) Significant negative correlation between APOE and ESR2 expression and ORM1 and SRY expression. The statistical significance of correlations was determined using Pearson’s correlation coefficient.