TABLE 4.

In vitro activity of contezolid and linezolid against strains with linezolid resistance genes.

Strains	Species	Drug-resistant genes	MIC (μg/mL)
			Contezolid	Linezolid
103	Staphylococcus capitis	cfr	>16	>16
124	Staphylococcus capitis	cfr	>16	>16
127	Staphylococcus capitis	cfr	>16	>16
146	Staphylococcus capitis	cfr	>16	>16
161	Staphylococcus capitis	cfr	>16	>16
24	Staphylococcus capitis	cfr	>16	>16
390	Staphylococcus capitis	cfr	>16	>16
323	Staphylococcus capitis	cfr	>16	>16
283	Staphylococcus capitis	cfr	>16	>16
XY-22	Enterococcus faecalis	optrA	2	4
XY-29	Enterococcus faecalis	optrA	1	1
XY-11	Enterococcus faecalis	optrA	2	2
LY-4	Enterococcus faecalis	optrA	1	2
SS27	Enterococcus faecalis	optrA	2	4
JH2-2	Enterococcus faecalis	optrA	1	1
XY-12	Enterococcus faecalis	optrA	1	2
XY-9	Enterococcus faecalis	optrA	1	2
LY-9	Enterococcus faecalis	optrA	1	2