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. 2021 Aug 19;8:723790. doi: 10.3389/fmed.2021.723790

Table 1.

Characteristics of the included studies.

References Country Setting Studied area Study type Sample size
(intervention vs. control)
Patient characteristics Intervention Control Duration (months)
Age * (year) Male (%) NAFLD diagnosis method DM (%)
Fard et al. (18) Iran Single school of Nursing and Midwifery Urban RCT 30 vs. 30 Intervention 40.3
Control 38.3
76.3% Ultrasound 0% Telephone Usual care 3
Axley et al. (19) USA Department of Internal Medicine, University of Texas Medical Urban RCT 13 vs. 17 Intervention 54 ± 2.7
Control 52 ± 2.3
33% Ultrasound, elevate liver enzyme Intervention 38%
Control 30%
Text messaging Usual care 6
Vilar-Gomez et al. (20) USA 4 Universities NA Non-RCT 157 vs. 38 Intervention 53.8 ± 8.4
Control 52.3 ± 9.5
37% Non-invasive scores 100% On-site education classes or via web-based Usual care 12
Mazzotti et al. (17) Italy Unit of Metabolic Diseases and Clinical
Dietetics, University of Bologna
Urban and rural Non-RCT 278 vs. 438 Intervention web-treated 46.0 ± 11.5
Intervention group-treated 55.1 ± 12.3
53.5% Ultrasound Intervention web-treated 21.6%
Intervention group-treated 40.6%
Web-based program Group-base program 24

DM, diabetes mellitus; NA, not available; NAFLD, non-alcoholic fatty liver disease; RCT, randomized controlled trial; USA, United States of America.

*

Values are presented as mean ± standard deviation.