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. 2021 Aug 19;11:680643. doi: 10.3389/fcimb.2021.680643

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Copyright © 2021 Zhao, Chen, Gao, Wu, Li, Wang, Huang, Cui, Du and Ying

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison between patients with recurrent spontaneous abortion (RSA) and controls. The effect size for each differentially abundant taxon was computed using linear discriminant analysis (LDA), which indicated its contribution to group differentiation. OTUs are presented in red and green when the taxa were significantly more abundant in the controls and RSA, respectively. (A) Differentially abundant vaginal taxa detected in patients not taking any medicine and controls. (B) Differentially abundant taxa detected in patients who did take medicine and controls.