Table 2.

Results from nonparametric MANOVA analysis based on UniFrac distance.

Comparison	p-value (UniFrac distance)
	Unweighted	Weighted
NM vs. Control	0.012	0.498
DT vs. Control	0.021	0.287
NM vs. DT	0.487	0.174
Metformin vs. Control	0.534	0.518
Aspirin plus Metformin vs. Control	0.078	0.270
Other medication vs. Control	0.033	0.467
Aspirin plus Metformin vs. Other medication	0.543	0.295
Aspirin plus Metformin vs. Metformin	0.540	0.540
Metformin vs. Other medication	0.349	0.866

NM, no medication; DT, drug treatment.