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. 2021 Aug 19;9:625877. doi: 10.3389/fbioe.2021.625877

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Copyright © 2021 Wang, Mei, Jiang, Jin, Xu, Li, Li, Meng, Zhu and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Surface morphology and component characterization of Ti–M–H coatings. (A) Coating morphology via scanning electron microscopy. (B) Roughness analysis on the coating surface. (C) Sample surface wettability test. (D) Amount of Ca ion release after 1 day of immersion in phosphate-buffered saline. (E) The amount of P ion released after 1 day of immersion in PBS. *P < 0.05 compared with Ti–M. ^#P < 0.05 compared with Ti–M–H1. ^&P < 0.05 compared with Ti–M–H4. **P < 0.01 compared with Ti–M. ^##P < 0.01 compared with Ti–M–H1. ^&&P < 0.01 compared with Ti–M–H4. The experiments were repeated three times.