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. 2021 Aug 19;11:715173. doi: 10.3389/fonc.2021.715173

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Copyright © 2021 Han, Wu, Zhao, Gong and Shen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemical staining for protein expression of MCMs in tissues from patients with SKCM and normal tissues. The results revealed MCM1–7 protein levels were higher in melanoma tissues than in normal skin tissues, consistent with the results of MCM mRNA expression, whereas MCM9 and MCM10 proteins showed no great difference between melanoma and normal skin.