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Genetic mutations in MCM family members (cBioPortal). (A) A visual summary of alteration based on a query of 10 MCMs, which was altered in 255 samples out of 444 SKCM patients (57.43%). (B) MCM1 (SRF) (19%) was the most frequently altered gene among the MCM genes, followed by MCM3 (17%), MCM4 (13%), and MCM7 (13%), including amplification, deep deletion, and missense mutations.
