Table 1.
Clinicopathological findings in stage II and III colorectal cancer.
| Cohort 1 (%) | Cohort 2 (%) | |||||
|---|---|---|---|---|---|---|
| Total | 148 | 138 | p value | |||
| Age, median (range) (y) | 67.5 (34–94) | 70.0 (41–88) | 0.1583 | |||
| Sex | Man | 90 (60.8) | 81 (58.7) | 0.7193 | ||
| Woman | 58 (39.2) | 57 (41.3) | ||||
| Location | Right colon | 30 (20.3) | 32 (23.2) | 0.4271 | ||
| Left colon | 64 (43.2) | 49 (35.5) | ||||
| Rectum | 54 (36.5) | 57 (41.3) | ||||
| pT | pT3 | 129 (86.5) | 111 (80.4) | 0.1474 | ||
| pT4 | 19 (13.5) | 27 (19.6) | ||||
| Stage | II | 71 (48.0) | 69 (50.0) | 0.8129 | ||
| III | 77 (52.0) | 69 (50.0) | ||||
| Histological type | WDA | 17 (11.5) | 26 (18.8) | 0.0681 | ||
| MDA | 121 (81.8) | 109 (79.9) | ||||
| PDA | 2 (1.4) | 1 (0.7) | ||||
| PAP | 6 (4.1) | 1 (0.7) | ||||
| MUC | 2 (1.4) | 1 (0.7) | ||||
| Lymphatic invasion | Positive | 130 (87.8) | 129 (93.5) | 0.4404 | ||
| Negative | 18 (12.2) | 9 (6.5) | ||||
| Venous invasion | Positive | 129 (87.2) | 128 (92.8) | 0.4534 | ||
| Negative | 19 (12.8) | 10 (7.2) | ||||
| Tumor budding | Low | 117 (79.1) | 108 (78.3) | 0.8861 | ||
| High | 31 (20.9) | 30 (21.7) | ||||
| Desmoplastic reaction | Mature | 65 (43.9) | 61 (44.2) | 0.9877 | ||
| Intermediate | 53 (35.8) | 49 (35.5) | ||||
| Immature | 30 (20.3) | 28 (20.3) | ||||
| Disease-free survival, median (range) (d) | 1857 (33–3196) | 1835 (93–3308) | ||||
| Overall survival, median (range) (d) | 3077 (52–3196) | 2195 (93–3308) | ||||
WDA, well-differentiated adenocarcinoma; MDA, moderately differentiated adenocarcinoma; PDA, poorly differenced adenocarcinoma; PAP, papillary carcinoma; MUC, mucinous carcinoma.