Table 1.
Comparison of COVID-19 patients study parameters with healthy controls
| COVID-19 patients (n=74) | Healthy controls (n=33) | Total (n=107) |
p value | |
|---|---|---|---|---|
| Age | NS | |||
| Mean (SD) | 58.486 (14.430) | 54.333 (10.908) | 57.206 (13.529) | |
| Median (Q1,Q3) | 58.500 (47.500, 70.750) | 54.000 (48.000, 63.000) | 58.000 (48.000, 67.500) | |
| Min – Max | 19.000 - 84.000 | 23.000 - 72.000 | 19.000 - 84.000 | |
| Gender | NS | |||
| Female | 43 (58.1%) | 18 (54.5%) | 61 (57.0%) | |
| Male | 31 (41.9%) | 15 (45.5%) | 46 (43.0%) | |
| Serum cortisol | 0.034 | |||
| Mean (SD) | 16.443 (5.940) | 14.104 (4.772) | 15.721 (5.688) | |
| Median (Q1,Q3) | 15.655 (12.443, 20.617) | 13.520 (10.520, 17.150) | 15.000 (11.470, 18.910) | |
| Min – Max | 5.600 - 34.050 | 8.040 - 30.120 | 5.600 - 34.050 | |
| Serum ACTH | 0.002 | |||
| Mean (SD) | 23.408 (20.173) | 33.000 (19.551) | 26.366 (20.383) | |
| Median (Q1,Q3) | 17.000 (10.250, 31.400) | 27.000 (21.000, 40.000) | 21.000 (13.000, 33.000) | |
| Min – Max | 2.000 - 114.000 | 9.000 - 90.000 | 2.000 - 114.000 | |
| Cortisol/ACTH ratio | <0.001 | |||
| Mean (SD) | 12879.091 (12957.387) | 5507.039 (3396.952) | 10605.467 (11437.214) | |
| Median (Q1,Q3) | 8651.103 (5062.446, 14696.930) | 4203.226 (3558.824, 5876.000) | 6297.059 (4184.524, 12132.579) | |
| Min - Max | 1578.947 - 70333.333 | 1243.333 - 15522.222 |
NS: not significant.