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Basal locomotor activity in FFAR1+/+ and −/− mice in response to a novel environment. An open-field test for a total of 5 min showed a slight reduction in locomotion time (A) and path length (B) in −/− mice. However, significant differences in locomotion speed (C) and the percentage of the time spent in the center region (D) were noticed in the −/− mice. *p < 0.05, **p < 0.01 vs. +/+ mice (Student’s t-test). n = 15 per genotype.
