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. 2021 Aug 20;12:699813. doi: 10.3389/fpsyt.2021.699813

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Copyright © 2021 Park, Haak, Cho, Valk, Bethlehem, Milham, Bernhardt, Di Martino and Hong.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subcortical-primary sensory/motor network. Top right. Parcellations used for the seed-based functional connectivity analysis of within-primary sensory/motor and subcortical networks are shown. (See Materials and methods for details.) Bottom left. A heatmap representing correlation coefficients of intrinsic functional connectivity (iFC) in subcortical-primary/motor networks. Significant group differences are shown with asterisks (FDR = 0.05). Hypoconnectivity (ASD < NT) was found in the within-primary sensory/motor network, and hyperconnectivity (ASD > NT) was found between subcortical structures and sensory/motor cortices, collectively suggesting an atypical diverging pattern of iFC in ASD. L, left; R, right; NT, Neurotypical controls; ASD, Autism Spectrum Disorder.