Table 1.
Demographic and clinical data for the participates included in the study.
| Variable | Discovery Cohort | Validation Cohort | ||||
|---|---|---|---|---|---|---|
| MS (N = 10) | NINCs (N = 10) | MS (N = 40) | NINCs (N = 40) | HC (N = 40) | ||
| RRMS (N = 23) | SPMS (N = 17) | |||||
| N, CSF; Serum | 10; 0 | 10; 0 | 23; 23 | 17; 17 | 40; 0 | 0; 40 |
| Age (year), mean ± SD | 32.9 ± 10.4 | 41.9 ± 15.9 | 39.8 ± 14.0 | 33.1 ± 11.3 | 36.6 ± 9.9 | 38.2 ± 11.6 |
| Male (%) | 4 (40%) | 6 (60%) | 8 (34.8%) | 6 (35.3%) | 13 (32.5%) | 14 (35%) |
| Disease duration (year), mean ± SD | 4.3 ± 4.1 | – | 3.6 ± 3.8 | 14.2 ± 8.1 | – | – |
| EDSS, mean ± SD | 2.5 ± 1.2 | – | 2.8 ± 1.5 | 5.4 ± 1.2 | – | – |
| MRI lesion | – | – | – | |||
| 0-8 lesions, n, n% | 4, 40.0% | 13, 56.5% | 7, 41.2% | |||
| ≥9 lesions, n, n% | 6, 60.0% | 10, 43.5% | 10, 58.8% | |||