All Dose Levels, All Cycles
Name	NC/NA	1	2	3	4	5	All grades
Fatigue	61%	22%	17%	0%	0%	0%	39%
Nausea	78%	11%	11%	0%	0%	0%	22%
Alanine aminotransferase increased	83%	6%	0%	11%	0%	0%	17%
Aspartate aminotransferase increased	83%	6%	0%	11%	0%	0%	17%
Diarrhea	83%	11%	6%	0%	0%	0%	17%
Dry mouth	83%	17%	0%	0%	0%	0%	17%
Abdominal pain	89%	0%	0%	11%	0%	0%	11%
Blood alkaline phosphatase increased	89%	0%	0%	11%	0%	0%	11%
Constipation	89%	6%	6%	0%	0%	0%	11%
Decreased appetite	89%	6%	6%	0%	0%	0%	11%
Hypokalemia	89%	11%	0%	0%	0%	0%	11%
Hypomagnesemia	89%	11%	0%	0%	0%	0%	11%
Hypophosphatemia	89%	6%	0%	6%	0%	0%	11%
Hypothyroidism	89%	0%	11%	0%	0%	0%	11%
Lymphopenia	83%	0%	0%	11%	6%	0%	17%
Musculoskeletal chest pain	89%	11%	0%	0%	0%	0%	11%
Musculoskeletal stiffness	89%	11%	0%	0%	0%	0%	11%
Pain in extremity	89%	11%	0%	0%	0%	0%	11%
Rash maculo‐papular	89%	11%	0%	0%	0%	0%	11%
Salivary hypersecretion	89%	6%	6%	0%	0%	0%	11%
Skin abrasion	89%	6%	6%	0%	0%	0%	11%
Vomiting	89%	11%	0%	0%	0%	0%	11%

Adverse Events Legend

Adverse events occurring in ≥10% of patients are shown.

There were no DLTs.

Abbreviation: NC/NA, no change from baseline/no adverse event.