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. 2021 Jun 9;26(9):e1609–e1618. doi: 10.1002/onco.13822

Figure 4.

Figure 4

Association of RDI with OS in studies of FOLFOX‐, FOLFIRI‐, or FOLFIRINOX‐based and carboplatin‐based regimens. *, Kobayashi et al. (2019) evaluated 5‐flurouracil infusion as part of an evaluation of constituents of FOLFIRINOX. Abbreviations: CI, confidence interval; CRC, colorectal cancer; FOLFIRI, folinic acid (leucovorin), fluorouracil (5‐FU), and irinotecan; FOLIRINOX, folinic acid (leucovorin), fluorouracil (5‐FU), irinotecan, and oxaliplatin; HR, hazard ratio; mFOLFOX6, modified folinic acid (leucovorin), fluorouracil (5‐FU), and oxaliplatin (six cycles postoperative); NSCLC, non‐small cell lung cancer; OS, overall survival; RDI, relative dose intensity; seTE, standard error of treatment effect; TE, treatment effect.