TABLE 4.
Placental iron transporter gene and protein expression among women who were obese and nonobese prepregnancy1
| Variable | Obese women (n = 18) | Nonobese women (n = 19) | P value |
|---|---|---|---|
| Transferrin receptor mRNA, –ΔCt (GCM1-TFR1) | 1.85 (1.38–2.32) | 1.37 (0.91–1.83) | 0.15 |
| Transferrin receptor protein/β-actin | 0.93 (0.79–1.07) | 1.07 (0.94–1.21) | 0.15 |
| Ferroportin mRNA, –ΔCt (GCM1-FPN) | 1.02 (0.61–1.44) | 0.67 (0.26–1.07) | 0.22 |
| Ferroportin protein/β-actin | 0.90 (0.82–0.98) | 0.94 (0.86–1.02) | 0.52 |
1
Data are presented as least squares means (95% CIs) from generalized linear models (proc GLM). Statistical significance was set at P < 0.05. FPN, ferroportin; GCM1, glial cells missing transcription factor 1; TFR1, transferrin receptor 1.