TABLE 3.
Iron regulatory hormone concentrations and hormone concentration ratios in newborns born to women carrying multiple fetuses and teens carrying singletons at birth1
| Variable | n | Whole population | n | Multiples cohort | n | Teen cohort |
|---|---|---|---|---|---|---|
| ERFE, ng/mL | 291 | 0.73 (0.63, 0.85) | 127 | 0.77 (0.62, 0.94) | 164 | 0.71 (0.57, 0.88) |
| EPO, mIU/mL | 273 | 24.15 (21.81, 26.73) | 124 | 17.4 (15.1, 20.0) | 150 | 31.7 (27.8, 36.1)3 |
| Hepcidin,2 ng/mL | — | — | 126 | 13.6 (11.4, 16.4) | 161 | 96.4 (84.8, 109.7) |
| Std hep | 287 | −0.008 ± 0.99 | 126 | 0.04 ± 0.4 | 161 | 0.08 ± 0.3 |
| Hep:EPO2 | — | — | 124 | 0.8 (0.6, 1.0) | 149 | 3.1 (2.6, 3.9) |
| Std hep:EPO | 272 | −0.59 ± 14.39 | 126 | −0.002 ± 0.08 | 149 | 0.007 ± 0.08 |
| Hep:ERFE2 | — | — | 126 | 18.0 (13.2, 24.5) | 161 | 136 (105, 177) |
| Std hep:ERFE | 287 | 0.003 ± 0.08 | 126 | 0.2 ± 2.4 | 161 | −1.2 ± 19.1 |
| ERFE:EPO | 273 | 0.03 (0.03, 0.04) | 124 | 0.04 (0.04, 0.05) | 150 | 0.02 (0.02, 0.03)3 |
1
Values are geometric means (95% CIs) unless otherwise indicated. EPO, erythropoietin; ERFE, erythroferrone; Hep, hepcidin.
2
Differences between cohorts were not assessed because Hep values were measured with different assays.
3
Significant difference between cohorts, P < 0.05.