Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Aug 20;13:716917. doi: 10.3389/fnagi.2021.716917

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Xu, Du, Jiang, Yang, Wang, Wang, Tang, Fu and Hao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Angiotensin II-induced hypertension upregulates the expression of microglial marker and promotes the activation of M1 microglial transformation in middle-aged mice. (A) Representative images of brain slices stained with the anti-IBA1 (green) and anti-CD68 antibodies (red) in the cortex and hippocampus (CA1, DG, and CA3) of mice in the control and hypertension groups (immunofluorescence, ×20, scale bar = 50 μm). (B) Histograms comparing the number of IBA1-positive cells in the cortex and hippocampus (CA1, DG, and CA3) of mice in the control and hypertension groups. (C) Histograms comparing the number of CD68-positive cells in the cortex and hippocampus (CA1, DG, and CA3) of mice in the control and hypertension groups. Data are expressed as the means ± SD. * p < 0.05.