Table 2.

Association between circulating miR-1290 expression and clinicopathologic characteristics in 46 pancreatic cancer patients

Variable	Total (n = 46)	miR-1290 expression		p value
		Low (n = 13)	High (n = 33)
Age (year)	65.48 ± 1.77	69.15 ± 3.53	64.03 ± 2.01	0.195
Sex				0.975
Male	32	9	23
Female	14	4	10
BMI (kg/m2)	22.01 (19.69–25.40)	23.26 (20.00–26.88)	21.97 (19.16–25.13)	0.518
Smoke				0.057
Yes	17	2	15
No	29	11	18
Alcohol				0.164
Yes	14	2	12
No	32	11	21
Hypertension				0.818
Yes	20	6	14
No	26	7	19
Diabetes				0.813
Yes	13	4	9
No	33	9	24
Location				0.894
Head	29	8	21
Body and tail	17	5	12
Tumor size (cm)	3.55 (2.32–4.53)	2.30 (1.80–2.80)	4.00 (2.87–4.60)	0.002**
Lymphatic invasion				0.003**
Positive	35	6	29
Negative	11	7	4
Venous invasion				0.030*
Positive	32	6	26
Negative	14	7	7
Distant metastasis				0.022*
Positive	23	3	20
Negative	23	10	13
Differentiation				0.036*
Well	7	3	4
Moderate	22	9	13
Poor	17	1	16
TNM stage (AJCC)				0.022*
I and II	23	10	13
III and IV	23	3	20
CRP (mg/l)				0.624
< 10	33	10	23
≥ 10	13	3	10
CEA (ng/ml)				0.295
< 5	30	10	20
≥ 5	16	3	13
CA199 (U/ml)
< 37	6	2	4	0.767
≥ 37	40	11	29
CA125 (U/ml)				0.146
< 35	24	9	15
≥ 35	22	4	18
CA242 (U/ml)				0.720
< 20	16	4	12
≥ 20	30	9	21
CA211 (ng/ml)				0.299
< 5	34	11	23
≥ 5	12	2	10

* p < 0.05, ** p < 0.01