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. 2021 Sep 3;13:148. doi: 10.1186/s13195-021-00887-4

Fig. 2.

Fig. 2

Predicted mean trajectories over time (plain line) and associated 95% confidence intervals (shades) of the underlying cognitive ability and functional dependency according to the clinical stage (CN, MCI, and AD) and education; trajectories are displayed for non-APOE ε4 carriers; male sex and aged between 82.60 and 85.12. Ninety-five percent confidence intervals were obtained using a Monte Carlo method with 2000 draws