Table 1.
Characteristics of participants at baseline (n = 297), COGICARE study
| CN | MCI | AD | All | |
|---|---|---|---|---|
| (N = 102) | (N = 123) | (N = 72) | (N = 297) | |
| Age in years: median (min–max) | 83.4 (75.6–92.8) | 82.0 (74.2–95.2) | 84.4 (76.0–93.5) | 82.9 (74.2–95.2) |
| Male sex (%) | 32.35 | 41.46 | 34.72 | 36.70 |
| Education level higher than primary school (%) | 77.45 | 65.85 | 62.50 | 69.02 |
| ApoE4 carriers (%) | 14.71 | 13.82 | 36.11 | 19.53 |
| Limitation in activities of daily living (%): | ||||
| Bathing | ||||
| No limitation | 96.08 | 95.93 | 66.67 | 88.89 |
| Partial limitation | 1.96 | 2.44 | 16.67 | 5.72 |
| Total limitation | 1.96 | 1.63 | 16.67 | 5.39 |
| Dressing | ||||
| No limitation | 96.08 | 97.56 | 73.61 | 91.25 |
| Partial limitation | 0.98 | 1.63 | 13.89 | 4.38 |
| Total Limitation | 2.94 | 0.81 | 12.50 | 4.38 |
| Toileting | ||||
| No limitation | 100.00 | 99.19 | 95.83 | 98.65 |
| Partial limitation | 0.00 | 0.00 | 4.17 | 1.01 |
| Total limitation | 0.00 | 0.81 | 0.00 | 0.34 |
| Transfering | ||||
| No limitation | 99.02 | 99.19 | 94.44 | 97.98 |
| Partial limitation | 0.98 | 0.81 | 5.56 | 2.02 |
| Total limitation | 0.00 | 0.00 | 0.00 | 0.00 |
| Eating | ||||
| No limitation | 99.02 | 100.00 | 95.83 | 98.65 |
| Partial limitation | 0.98 | 0.00 | 4.17 | 1.35 |
| Total limitation | 0.00 | 0.00 | 0.00 | 0.00 |
| Limitation in instrumental activities of daily living (%): | ||||
| Telephone use | ||||
| No limitation | 100.00 | 95.12 | 56.94 | 87.54 |
| Partial limitation | 0.00 | 4.88 | 36.11 | 10.77 |
| Total limitation | 0.00 | 0.00 | 6.94 | 1.68 |
| Shopping | ||||
| No limitation | 78.43 | 77.24 | 36.11 | 67.68 |
| Partial limitation | 13.73 | 19.51 | 26.39 | 19.19 |
| Total limitation | 7.84 | 3.25 | 37.50 | 13.13 |
| Transportation | ||||
| No limitation | 79.41 | 83.74 | 44.44 | 72.73 |
| Partial limitation | 19.61 | 15.45 | 48.61 | 24.92 |
| Total limitation | 0.98 | 0.81 | 6.94 | 2.36 |
| Medication | ||||
| No limitation | 99.02 | 95.12 | 48.61 | 85.19 |
| Partial limitation | 0.00 | 4.07 | 25.00 | 7.74 |
| Total limitation | 0.98 | 0.81 | 26.39 | 7.07 |
| Finances | ||||
| No limitation | 89.22 | 86.99 | 41.67 | 76.77 |
| Partial limitation | 10.78 | 11.38 | 26.39 | 14.81 |
| Total limitation | 0.00 | 1.63 | 31.94 | 8.42 |
| Cognitive scores: median (min–max) | ||||
| MMSE | 28 (17–30) | 27 (20–30) | 23 (11–28) | 27 (11–30) |
| IST | 45 (22–82) | 39 20–61) | 29 (12–62) | 39 (12–82) |
| BVRT | 12 (6–15) | 11 (5–15) | 9 (5–14) | 11 (5–15) |
| TMT-B | 26.5 (3.0–60.0) | 21.3 (0.5–62.6) | 7.3 (0.7–40.0) | 20.0 (0.5–62.6) |
| Limitation score: median (min–max) | 0 (0–7) | 0 (0–14) | 3 (0–13) | 0 (0–14) |
| Number of measures by subject over follow-up: median (min–max) | ||||
| MMSE | 5 (2–6) | 5 (2–7) | 4 (1–7) | 5 (1–7) |
| IST | 4 (1–6) | 5 (1–7) | 4 (1–7) | 4 (1–7) |
| BVRT | 2 (1–4) | 5 (2–6) | 3 (1–7) | 3 (1–7) |
| TMT-B | 2 (1–2) | 1 (1–2) | 1 (1–2) | 1 (1–2) |
| Limitations | 5 (2–6) | 5 (2–7) | 5 (2–7) | 5 (2–7) |