Table 3.
Different types of vaginal microbiota diversity clusters in pregnant women in the sub-Saharan African region
| Included articles that used VMB clustering | Price et al. | Gudza et al. | Brabin et al. | Borgdorff et al. | Gautam et al. | Frank et al. | Donders et al. |
|---|---|---|---|---|---|---|---|
| Name of cluster | Community state type (CST) | ClusterR | Cluster KRST | Genus-level clustering | morpho-types grades | ||
| Diversity group: Higher proportions of strictly anaerobic bacteria, including Prevotella, Dialister, Atopobium, Gardnerella, Megasphaera, Peptoniphilus, Sneathia, Eggerthella, Aerococcus, Finegoldia, and Mobiluncus. | CST-IV | ||||||
| Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1 and the presence of a lower abundance of L. iners. | R-III | KRST-III | |||||
| Diversity group: Higher proportions of strictly anaerobic bacteria, especially G vaginalis, BVAB1. | CST-IVA | ||||||
| Diversity group: Higher proportions of strictly anaerobic bacteria, especially G vaginalis, L iners, and A vaginae. | CST-IVB | ||||||
| Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, L. iners, and high abundance Gardnerella genus. | CST-IV-I | R-IV | KRST-IV | ||||
| Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, and lower total bacterial abundance than the other mixed anaerobic clusters. | R-V | KRST-V | |||||
| Diversity group: High abundances of Gardnerella, Prevotella and Atopobium species and lower abundances of Dialister, Megasphaera and Mobiluncus species and BVAB1, L. iners, and highest levels of Prevotella species. | R-VI | KRST-VI | |||||
| Diversity group: Higher proportions of strictly anaerobic bacteria and G. vaginalis, and A. vaginae. | CST-IV-II | ||||||
| Diversity group: Higher proportions of strictly anaerobic bacteria other than G. vaginalis and A. vaginae. | CST-IV-III | ||||||
| Diversity group: pooled dysbiotic clusters. | KRST-pIII-V | ||||||
| Diversity group: Mixed of variety of genera, dominated by Gardnerella spp. and Lactobacillus spp. | Cluster 3 | ||||||
| Diversity group: low Lactobacillus spp. and diverse anaerobic groups (eg, Prevotella, Sneathia, Peptostreptococcus) | Cluster 4 | ||||||
| Diversity group: lesser Lactobacillus spp mixed with other bacteria. | Grade II | ||||||
| Diversity group: Absence of Lactobacillus spp or overwhelming presence of other bacteria (not specified). | CST IV | Grade III | |||||
| Diversity group: Dominated by coagulase-negative staphylococci (S. haemolyticus and S. epidermidis) with lesser quantities of lactobacilli | Cluster 2 | ||||||
CST community state types numeric system described by Ravel et al., [2]. R-clusters, vaginal microbiota cluster method in Rwandese women as described in Borgdorff et al. [36]. KRST-clusters, vaginal microbiota cluster method in Kenyan, Rwandese, South African and Tanzanian women as describe in Gautam et al. [8]