Table 3.

Characteristics of the Test Cohort and performance of the Detection Algorithm for all the patients and the two age groups, for the two different operating points of the algorithm (“FDA-cleared” mode and “Active” mode, and for all the data (“All data”) vs. only periods of rest (“Automatically-Detected Rest”).

		All data			Automatically-detected rest
		Overall	Pediatric	Adult	Overall	Pediatric	Adult
Test cohort	# Patients (w/ CS)	152 (36)	85 (18)	67 (18)	144 (13)	78 (7)	66 (6)
	Total hours	10,296	3,939	6,357	3,995	1,703	2,292
	Average hours/pat.	68	46	95	26	20	34
	Total CS	66	35	31	20	13	7
	Mean duration [sec] (St. Dev.)	84.56 (34.57)	89.37 (39.09)	79.13 (28.27)	78.65 (26.49)	79.61 (24.25)	76.86 (32.26)
“FDA-cleared” mode	Detected CS	65	34	31	19	12	7
	Mean delay [sec] (St. Dev.)	37.46 (21.09)	37.76 (24.06)	37.13 (17.64)	33.05 (12.09)	32.08 (7.77)	34.71 (17.96)
	Sensitivity	0.98	0.97	1.00	0.90	0.92	1.00
	cSensitivity [95% CI]	0.96 [0.92, 1.00]	0.92 [0.85, 1.00]	0.94 [0.89, 1.00]	0.83 [0.69, 0.97]	0.82 [0.65, 0.99]	0.82 [0.65, 1.00]
	Precision [95% CI]	0.15 [0.12, 0.19]	0.14 [0.10, 0.19]	0.17 [0.12, 0.23]	0.95* [0.76, 0.99]	0.93* [0.66, 0.99]	0.89* [0.52, 0.98]
	Total false alarms	357	207	150	0	0	0
	FAR [95% CI]	0.83 [0.63, 1.07]	1.26 [0.87, 1.73]	0.57 [0.36, 0.81]	0	0	0
“Active” mode	Detected CS	63	32	31	19	12	7
	Mean Delay [sec] (St. Dev.)	40.03 (16.25)	37.44 (12.96)	42.71 (18.91)	38.26 (12.43)	36.75 (7.62)	40.86 (18.57)
	Sensitivity	0.95	0.91	1.00	0.90	0.92	1.00
	cSensitivity [95% CI]	0.91 [0.84, 0.99]	0.85 [0.72, 0.98]	0.94 [0.89, 1.00]	0.83 [0.69, 0.97]	0.82 [0.65, 0.99]	0.82 [0.65, 1.00]
	Precision [95% CI]	0.36 [0.29, 0.43]	0.33 [0.24, 0.43]	0.39 [0.29, 0.50]	0.95* [0.76, 0.99]	0.93* [0.66, 0.99]	0.89* [0.52, 0.98]
	Total false alarms	113	65	48	0	0	0
	FAR [95% CI]	0.27 [0.18, 0.36]	0.40 [0.23, 0.59]	0.18 [0.10, 0.28]	0	0	0

CI, Confidence Interval. *Laplace correction (i.e., the “rule of succession”) was applied to improve the estimation of the precision and its 95% confidence interval.