Table 3.
The summary of the common genes of the five pathways in cancer cells treated with three TCM candidates.
| Pathway | Common genes in medicine | Regulate |
|---|---|---|
| TNF signaling pathway | IL6 | upregulated |
| LIF | upregulated | |
| PIK3R1 | downregulated | |
| PIK3R3 | upregulated | |
| IL−17 signaling pathway | IL6 | upregulated |
| FOSL1 | upregulated | |
| TNFAIP3 | upregulated | |
| S100A9 | upregulated | |
| NF-kappa B signaling pathway | CXCL12 | downregulated |
| LYN | upregulated | |
| NFKBIA | upregulated | |
| TNFAIP3 | upregulated | |
| BRIC3 | upregulated | |
| EDARADD | upregulated | |
| Transcriptional misregulation in cancer | IL6 | upregulated |
| BIRC3 | upregulated | |
| CDKN2C | downregulated | |
| ID2 | downregulated | |
| PLAT | upregulated | |
| PPARG | upregulated | |
| CEBPB | upregulated | |
| MAPK signaling pathway | RPS6KA3 | upregulated |
| AREG | upregulated | |
| DUSP6 | upregulated | |
| EPHA2 | upregulated |