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. 2021 Aug 13;12:691811. doi: 10.3389/fimmu.2021.691811

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Copyright © 2021 Zhang, Zhang, Wang, Dai, Zhang, Cheng and Liu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TME landscape in gliomas and characteristics of TME subtypes in the meta-cohort. (A) Cellular interaction of the TME cell types. (B) Unsupervised clustering of TME cells for 2877 patients in the meta-cohort. (C) Kaplan–Meier curves for two TME groups of 2877 patients in the meta-cohort. Log-rank test, P < 0.001. (D) PCA separated the two TME clusters. (E) Fraction of TME cells in two TME clusters. The scattered dots represent TME cell expression values within each group. NS, Not Statistically Significant; **P < 0.01; ****P < 0.0001.