Table 1.
Agent | Dose/s | Period | Comment |
---|---|---|---|
Haloperidol (HAL) | Up to 10 mg/d | 2015 (4 mths) 2018 (1 mth) 2020 (2 wks)* |
Combined with diazepam improved the most distressing hallucinations but caused intolerable extrapyramidal side effects (EPS). |
Risperidone (RIS) | 6 mg/d | 2015–2016 (~1 year) | Partially relieved the positive symptoms despite suspected concomitant drug use, but caused EPS and ejaculatory dysfunction. It was replaced by Clozapine, and after a second attempt (4 mths in 2017 during a later admission event) by Quetiapine. |
Olanzapine (OLA) | Up to 30 mg/d prn 7.5–15 mg during exacerbations |
2018 (2 mths) | Good sedative effect and transiently improved hallucinations and delusions. |
Clozapine | Up to 700 mg/d | 2015–2018 (~3 yrs) | The most effective medication according to the medical staff. The patient reported asymptomatic periods alternating with periods of controllable symptoms, though never a permanent relief. |
Quetiapine (QUE) | 900 mg/d | Current | The most effective medication according to the patient, particularly against hallucinations and anxiety, but still without a permanent relief as monotherapy. |
Aripiprazole | Up to 30 mg/d | 2017 (3 wks, October) | The patient refused to continue with it and stated that “it was not good” for him, without further explanation. |
Lithium | Up to 210 mg/d | 2018 (October) - current | Used as a calming agent. |
Discussed in the current report.