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. 2021 Aug 19;12:703693. doi: 10.3389/fmicb.2021.703693

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Copyright © 2021 Yang, Liu, Wang, Robinson, Whitmore, Stewart, Zhao and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Relative abundances of representative ileal bacteria showing a significant correlation with the severity of NE. Ileal bacteria were significantly enriched (A), progressively declined (B), or abruptly abolished (C) in response to NE. In the box and whisker plots, each box indicates median, 25 and 75th percentiles, while whiskers extend to 1.5 interquartile range. Significance was measured using the Kruskal-Wallis test and indicated on the top of each plot. Pairwise comparisons were further implemented using the Wilcoxon rank sum test, and the significance (p<0.05) was denoted by different superscripts.