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. 2021 Apr 2;144(8):2349–2360. doi: 10.1093/brain/awab110

Figure 1.

Figure 1

Accumulation of glycogen in the brains of 3-month-old mice. Lafora bodies are abundant in malinKO hippocampi but greatly diminished in malinKO+MGSGfap-KO hippocampi. (A) Low and high power photomicrographs illustrating the distribution of Lafora bodies after periodic acid-Schiff (PAS) staining and MGS immunostaining of the hippocampi of 3-month-old littermates from the different groups. Scale bar = 100 μm. (B) Glycogen content of total brain. Control (n =7), malinKO (n =7), malinKO+MGSGfap-KO (n = 6). Data are expressed as mean ± SEM. ****P < 0.0001.